Publication details

The elderly and cardiovascular medication



Year of publication 2012
Type Article in Periodical
Magazine / Source Kuprevich Gerontological Journal
MU Faculty or unit

Faculty of Medicine

Field Other specializations of internal medicine
Keywords angiotensin converting enzyme inhibitors – antiaggregants – beta-blockers – statins – calcium blockers – diuretics – digoxin – pharmacotherapy in the elderly – unwanted side effects – medical interactions
Description Authors analyze actual situation in treatment of cardiovascular diseases in older patients. Different groups of recommended drugs are discussed separately, possible risks for elderly patients are stressed. Angiotensin converting enzyme inhibitors – this group is widely used in older patients because of their hypotensive effect, positive influence on cardiac failure and positive modulation of endothelial dysfunction. The risk of hyperkalemia must be considered. Antiaggregants and anticoagulants are proved as potent prophylactic treatment, but the associated risk of gastrointestinal bleeding must be weighed very carefully. Bradycardia related to beta-blockers, especially in combination with other medications lowering the heart rate must be taken into account, otherwise this group brings the highest profit in cardiovascular diseases as for morbidity and mortality. Attention is paid to calcium channel blockers, statines, diuretics, nitrates and digoxin. A table listing the possible side effects and clinical symptoms of overdose by medications most frequently used in the elderly concludes the article.
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