Publication details
Screening rizika malnutrice versus ukazatelé nutričního stavu a systémové zánětlivé odpovědi u pacientů s nově diagnostikovaným karcinomem plic
| Title in English | Screening of Malnutrition Risk Versus Indicators of Nutritional Status and Systemic Infl ammatory Response in Newly Dia gnosed Lung Cancer Patients |
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| Authors | |
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Klinická onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Pneumology |
| Keywords | nutritional screening; nutritional risk; lung cancer; acute phase response |
| Description | Background: Most lung cancers are already advanced at the time of dia gnosis. In these patients, a frequent symptom is protein-energy malnutrition, often dia gnosed prior to oncological treatment. Malnutrition results in poor tolerance of treatment and increased morbidity and mortality. Methods: Nutritional Risk Screening (NRS) 2002 adapted for oncological patients was used to assess the risk of undernutrition in a group of 188 lung cancer patients. The risk was evaluated on a 6- point scale according to common signs of nutritional status and tumor and its treatment risk factors. A score of 3 and more (called „nutritional risk“) means a signifi cant risk of malnutrition. Furthermore, pretreatment nutritional characteristics were evaluated in patients (including the value of BMI) and laboratory values indicating malnutrition/ acute phase response (albumin/ C- reactive protein – CRP). Results: Acceptable NRS score was found in 50.6%, while in 45.3% was suggested into risk of malnutrition („nutritional risk“). Only 6.6% of our patients had a BMI less than 20 kg/ m2. Signifi cant diff erences in albumin and CRP values in various categories of NRS were confi rmed. Conclusion: Initial signs of cancer malnutrition may be overlooked in patients who fall within or above the range of BMI for adequate weight, although these patients may be at signifi cant risk of malnutrition. The indicators of nutritional status and systemic infl ammatory responses were signifi cantly associated with resulting values NRS score. |