Publication details
Použití optické koherenční tomografie u roztroušené sklerózy
| Title in English | The Use of Optical Coherence Tomography in Multiple Sclerosis |
|---|---|
| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Česká a Slovenská neurologie a neurochirurgie |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.14735/amcsnn201633 |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | optical coherence tomography; multiple sclerosis; retinal nerve fibre layer; total macular volume |
| Description | Optical coherence tomography is fast, non-invasive and reproducible imaging technique that provides detailed measurements of retinal structures. Retinal pathology in multiple sclerosis (MS) includes consequences of optic neuritis as well as diff use degenerative changes. Thinning of retinal nerve fi ber layer, decrease in total macular volume and loss of retinal ganglion cell layer correlate with visual acuity, brain atrophy measures and cognitive changes. Anterior visual pathway became a model of neuroaxonal injury in MS and is used to test neuroprotective eff ects of new therapies. The paper provides an overview of the physics of optical coherence tomography and its application in MS. |