Publication details

Nová antibiotika v klinické praxi a výzkumu

Title in English New antibiotics in the clinical practise and in the clinical trials


Year of publication 2016
Type Article in Periodical
Magazine / Source Klinická farmakologie a farmacie
MU Faculty or unit

Faculty of Medicine

Field Pharmacology and pharmaceutical chemistry
Keywords new antibiotics; research and development of drugs; marketing approval; resistance
Description Expanding of resistance of still susceptible strains of bacteria to antibiotics, associated with the increasing consumption of antibiotics in both human and veterinary medicine, is occurring faster than the marketing approvals and the implementation of new antibiotic molecules to clinical practice. The development of new antibiotic molecules is troublesome, expensive and timeconsuming. Inspite of this, 30 new antibiotic molecules were registered in the last 15 years and more than 10 molecules are in the process of phase III clinical trials. Therefore we can expect further new marketing approvals in the field of antimicrobial drugs in the upcoming years. The article briefly describes the new antibiotics approved since 2000. This review also summarizes the current status of clinical research in the field of antibiotics.
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