Publication details

Yeast Biosensors for Detection of Environmental Pollutants: Current State and Limitations

Authors

JARQUE ORTIZ Sergio BITTNER Michal BLÁHA Luděk HILSCHEROVÁ Klára

Year of publication 2016
Type Article in Periodical
Magazine / Source TRENDS IN BIOTECHNOLOGY
MU Faculty or unit

Faculty of Science

Citation
Web http://www.sciencedirect.com/science/article/pii/S0167779916000202
Doi http://dx.doi.org/10.1016/j.tibtech.2016.01.007
Field Biotechnology
Keywords BIOCHEMICAL OXYGEN-DEMAND; MEDIATED GENE-EXPRESSION; IN-VITRO ASSESSMENT; SACCHAROMYCES-CEREVISIAE; WASTE-WATER; ESTROGEN SCREEN; CHEMICAL-SUBSTANCES; RECEPTOR LIGANDS; ACTIVE-CHEMICALS; REPORTER ASSAY
Description Yeast biosensors have become suitable tools for the screening and detection of environmental pollutants because of their various advantages compared to other sensing technologies. On the other hand, many limitations remain with regard to their optimal performance and applicability in several contexts, such as low-concentration samples and on-site testing. This review summarizes the current state of yeast biosensors, with special focus on screening and assessment of environmental contaminants, discusses both pros and cons, and suggests steps towards their further development and effective use in the environmental assessment.
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