Publication details

Krátká léčba nivolumabem vyvolávající těžkou únavu s dlouhotrvající parciální odpovědí - kasuistiky

Title in English Short nivolumab causing severe fatigue with long-lasting partial response - a case reports
Authors

JAKUBÍKOVÁ Lenka ŠPELDOVÁ Jana TOMÍŠKOVÁ Marcela SKŘIČKOVÁ Jana

Year of publication 2017
Type Article in Periodical
Magazine / Source Onkologická revue
MU Faculty or unit

Faculty of Medicine

Citation
Field Pneumology
Keywords nivolumab; non-small cell lung cancer; side effects
Description The authors of the first part of the article summarize the current therapeutic results of nivolumab in both squamous and non-squamous lung cancer, as well as the safety profile of this type of immunotherapy, including recommendations for prevention and measures for the occurrence of side effects. In particular, adverse events, particularly weakness and exhaustion, were reported in^two selected patients who experienced a severe fatigue with the need for permanent discontinuation of treatment immediately after initiation of treatment with nivolumab, but two months after the last dose of immunotherapy, partial healing response that lasted for one year in both patients was observed.

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