Publication details

CrocoBLAST: Running BLAST efficiently in the age of next-generation sequencing

Authors

TRISTAO RAMOS Ravi José DE AZEVEDO MARTINS Allan Cézar DE AZEVEDO MARTINS Allan Cézar DA SILVA DELGADO Gabrielle DA SILVA DELGADO Gabrielle IONESCU Crina-Maria ÜRMÉNYI Peter Turán SILVA Rosane KOČA Jaroslav

Year of publication 2017
Type Article in Periodical
Magazine / Source Bioinformatics
MU Faculty or unit

Faculty of Science

Citation
Web https://academic.oup.com/bioinformatics/article-abstract/33/22/3648/4004881
Doi http://dx.doi.org/10.1093/bioinformatics/btx465
Keywords sequence analysis; genomics; genome annotation; BLAST
Description CrocoBLAST is a tool for dramatically speeding up BLAST+ execution on any computer. Alignments that would take days or weeks with NCBI BLAST+ can be run overnight with CrocoBLAST. Additionally, CrocoBLAST provides features critical for NGS data analysis, including: results identical to those of BLAST+; compatibility with any BLAST+ version; real-time information regarding calculation progress and remaining run time; access to partial alignment results; queueing, pausing, and resuming BLAST+ calculations without information loss. CrocoBLAST is freely available online, with ample documentation (webchem.ncbr.muni.cz/Platform/App/CrocoBLAST). No installation or user registration is required. CrocoBLAST is implemented in C, while the graphical user interface is implemented in Java. CrocoBLAST is supported under Linux and Windows, and can be run under Mac OS X in a Linux virtual machine.
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