Publication details

The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT

Authors

BEDNÁROVÁ Veronika KINCL Vladimír KAMÍNEK Milan VAŠINA Jiří PANOVSKÝ Roman MÁCHAL Jan

Year of publication 2019
Type Article in Periodical
Magazine / Source International Journal of Cardiovascular Imaging
MU Faculty or unit

Faculty of Medicine

Citation
Web http://dx.doi.org/10.1007/s10554-019-01535-7
Doi http://dx.doi.org/10.1007/s10554-019-01535-7
Keywords Myocardial perfusion; Thallium; Low-dose; CZT; SPECT; Prognostic value
Description The purpose of this study was to assess the prognostic value of ultra-low dose thallium myocardial perfusion imaging. Three hundred and sixty-six patients (245 men) underwent ultra-low dose stress-redistribution imaging on CZT SPECT camera GE Discovery NM 530c. The stress test was performed by bicycle ergometry or regadenoson injection. The activity of 0.5MBq (0.014mCi) Tl-201 chloride per kilogram of body weight was administered. The stress images were acquired immediately and redistribution images were taken after 3h. Patient follow-up was focused on combined end-point (death, myocardial infarction, unstable angina, revascularization and hospitalization for heart failure). Data analysis was performed from hospital database, with a mean period 23 months. Patients with revascularization within 1 month after SPECT was excluded as revascularization for diagnosis. Ischaemia on SPECT was found in 72 patients, 294 patients were without ischaemia. In patients with ischaemia there were 21 (29.2%) subjects with cardiac events, and 23 (7.9%) in patients without ischaemia (HR 4.15, 95% CI 2.30-7.51, p<0.0001). Ultra-low dose thallium perfusion imaging using CZT camera provides very good prognostic results in assessment of myocardial ischaemia.

You are running an old browser version. We recommend updating your browser to its latest version.

More info