Publication details

Lokální trombolýza v léčbě pacientů s hlubokou žilní trombózou: proč, komu a jak?

Title in English Local thrombolysis for deep vein thrombosis: why, for whom and how?
Authors

RADVAN Martin HUSTÝ Jakub FLORIÁNOVÁ Alena HOŘÁKOVÁ Kateřina KALA Petr

Year of publication 2020
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.casopisvnitrnilekarstvi.cz/artkey/vnl-202003-0001_local-thrombolysis-for-deep-vein-thrombosis-why-for-whom-and-how.php
Keywords deep vein thrombosis; local thrombolysis; thrombembolic disease; anticoagulation; posttrombotic syndrome; endovascular therapy; cava filter
Description Despite the progress achieved in prevention and therapy in recent decades, venous thromboembolic disorder still presents medical burden. Incidence is estimated about 100-200/100 000 per year. Patients, who underwent deep vein thrombosis are at risk of recurrence and/or development of post-thrombotic syndrome. Both can affect the quality of life. In acute phase of the disease anticoagulation and compression are effective therapy in most cases. But in severe clinical manifestations escalation of the therapy should be considered. Surgical embolectomy is possible, but complication rate is high. Endovascular approaches are viable option. Catheter directed local thrombolysis is effective not only in situation of limb emergency (phlegmasia). We summarize indications, technical approach and evidence for this specific treatment.

You are running an old browser version. We recommend updating your browser to its latest version.

More info