Publication details
Determination of a Novel Antimycobacterial Agent in a Single Drop of a Solution by Voltammetry at a Glassy Carbon Electrode
| Authors | |
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| Year of publication | 2017 |
| Type | Article in Proceedings |
| Conference | XXXVII MODERNI ELEKTROCHEMICKE METODY |
| Citation | |
| Keywords | I-hydroxy-N-(4-nitrophenyl)naphthalene-2-carboxamide; glassy carbon electrode; DP voltammetry; miniaturization |
| Description | One of the novel antimycobacterial agents from the group of hydroxynaphthalene carboxamides (namely I-hydroxy-X-(4-nitrophenyl)naphthalene-2-carboxamide) was investigated using voltammetric methods for the first time. The study was carried out at a glassy carbon electrode by methods of cathodic and anodic differential pulse voltammetry in micro volumns (20 mu L) of an aqueous solution at pH 7 containing 10% dimethyl sulfoxide and in a real matrix of a bacterial growth medium. The miniaturized method was compared with the macro volume determination. The presence of oxygen in micro volumes presents the biggest obstacle for the miniaturized method. |