Publication details

Snášenlivost antidepresiv, jejich multimodální působení a mechanismy jejich nežádoucích účinků

Title in English Tolerability of antidepressants, their multimodal effects and mechanisms of their side effects


Year of publication 2021
Type Article in Periodical
Magazine / Source Psychiatrie pro praxi
MU Faculty or unit

Faculty of Medicine

Keywords antidepressants; tolerance; trazodone; mirtazapine; vortioxetine; venlafaxin; SSRI
Description Antidepressants represent an essential and effective therapeutic approach in treating depressive disorders and many other neuropsychiatric diseases. This review article summarizes the most common side effects of the most commonly used antidepressants in the Czech Republic. These side effects usually have a logical explanation based on their receptor profileor pharmacokinetics. In this context, the advantages and disadvantages of these selected most commonly used antidepressants are summarized, especially in terms of tolerability and additive effects.
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