Publication details
Gabapentinoidy v perioperačním období
| Title in English | Gabapentinoids in the perioperative period |
|---|---|
| Authors | |
| Year of publication | 2021 |
| Type | Article in Periodical |
| Magazine / Source | Anesteziologie a intenzivní medicína |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.aimjournal.cz/artkey/aim-202101-0003_gabapentinoids-in-the-perioperative-period.php |
| Doi | http://dx.doi.org/10.36290/aim.2021.012 |
| Keywords | Evidence of risk; History of gabapentinoids; Multimodal analgesia; Perioperative period |
| Description | Multimodal analgesia is predicated on interactions of medicines whereby benefits of combination exceed the risks. Periope rative gabapentinoids have significant adverse effects. Gabapentinoids, when combined with opioids, confer even greater respiratory risk than opioids alone. Routine perioperative administration of gabapentinoids is not more recommended. New clinical trials to evaluate analgesic benefits of gabapentinoids on postoperative pain are very unlikely to provide any new evidence. © 2021, Czech Medical Association J.E. Purkyne. All rights reserved. |