Publication details

Biological half-life of bromine in the rat thyroid

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VOBECKÝ Miloslav BABICKÝ Arnošt LENER Jaroslav PAVELKA Stanislav

Year of publication 1997
Type Article in Periodical
Magazine / Source Physiological Research [IF=0.807 (1996); SCI #cit.<13>]
MU Faculty or unit

Faculty of Science

Field Endocrinology, diabetology, metabolism, nutrition
Keywords biological half-life; rat; thyroid; bromine
Description The biological half-life of bromine in the thyroid was determined by measuring the radioactivity of thyroids of animals which continuously received 82Br-labelled bromide in their food. The value of this half-life (110 h) is practically the same as the biological half-life of iodine. The rate of establishing the [I]/[Br] concentration ratio in the thyroid depends on the biological half-life of bromine. The mechanism of this process depends on the state of iodine supply.
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