Publication details
Olanzapine, but not haloperidol, exerts pronounced acute metabolic effects in the methylazoxymethanol rat model
Authors | |
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Year of publication | 2024 |
Type | Article in Periodical |
Magazine / Source | CNS NEUROSCIENCE & THERAPEUTICS |
MU Faculty or unit | |
Citation | |
Web | https://onlinelibrary.wiley.com/doi/10.1111/cns.14565 |
Doi | http://dx.doi.org/10.1111/cns.14565 |
Keywords | adipokine; antipsychotic; lipid profile; methylazoxymethanol; schizophrenia |
Attached files | |
Description | Our results demonstrate metabolic vulnerability in female prenatally MAM-exposed rats indicating that findings from healthy animals are likely to provide an underestimated impression of metabolic dysfunction associated with antipsychotics. In the context of metabolic disturbances, neurodevelopmental models possess a relevant background, and the search for adequate animal models should receive more attention within the field of experimental psychopharmacology. |
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