Publication details

Customizing subcutaneous immunoglobulin administration in primary antibody deficiency: patient-centric care perspectives

Authors

KOBAYASHI Roger H MALTESE Joanna LITZMAN Jiří KREUWEL Huub ZEKOLL Theresa KOBAYASHI Ai Lan GUPTA Sudhir

Year of publication 2024
Type Article in Periodical
Magazine / Source IMMUNOTHERAPY
MU Faculty or unit

Faculty of Medicine

Citation
web https://www.tandfonline.com/doi/full/10.1080/1750743X.2024.2436343
Doi https://doi.org/10.1080/1750743X.2024.2436343
Keywords Immunoglobulin replacement therapy; patient-centric; primary antibody deficiency disease; shared decision-making; subcutaneous immunoglobulin; Cutaquig
Description This report delves into the challenges and potential solutions associated with flexible, customized subcutaneous immunoglobulin (SCIG) infusion regimens for patients with primary antibody deficiency disease (PAD). Advances in the treatment of inborn errors of immunity, particularly PAD, have converted fatal diseases into chronic, complex, long-term conditions that make adherence to treatment a critical issue. Conventional SCIG infusion regimens, while clinically effective, may not always align with the varied lifestyles, changing lifestyles and commitments of patients which can lead to missed doses, diminishing adherence thus posing potential health risks and compromising the overall effectiveness of treatment. For these reasons, it's important to develop flexible infusion regimens tailored to meet individual patient needs. Patient-centric strategies that promote shared decision-making and awareness of patient status not only promote medical efficacy but also enhance the overall patient experience. The authors of this report call attention for a need to shift toward more adaptable and individualized SCIG treatment plans for PAD patients whose needs may change over the long-term course of treatment.

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