Publication details
Opinion: Defining Readiness for Reconstructive Surgery in Patients With Advanced Pressure Ulcers—A Policy and Clinical Perspective
| Authors | |
|---|---|
| Year of publication | 2025 |
| Type | Article in Periodical |
| Magazine / Source | WOUND REPAIR AND REGENERATION |
| MU Faculty or unit | |
| Citation | |
| web | https://pmc.ncbi.nlm.nih.gov/articles/PMC12502464/ |
| Doi | https://doi.org/10.1111/wrr.70099 |
| Keywords | pressure ulcers; flap surgery; guidelines; nutrition |
| Description | The article “Defining Readiness for Reconstructive Surgery in Patients With Advanced Pressure Ulcers—A Policy and Clinical Perspective” (Hokynková A. et al., Wound Repair and Regeneration, 2025) addresses one of the key challenges in reconstructive surgery for pressure ulcers—the persistently high rates of flap-related complications and recurrences. The authors highlight the current lack of clear, evidence-based laboratory criteria defining patient readiness for elective reconstruction, which are not specified even in recent international guidelines (NPIAP/EPUAP/PPPIA 2025, WHS 2023, ESPEN). Based on long-term clinical experience, they propose pragmatic institutional thresholds adopted at the University Hospital Brno (Hb > 100 g/L, CRP < 50 mg/L, total protein > 60 g/L, albumin > 30 g/L, prealbumin > 0.15 g/L) to guide surgical timing and optimize outcomes. The paper calls for multicentre collaboration to validate standardized readiness criteria integrating nutritional, inflammatory, and metabolic parameters to improve safety and reproducibility in reconstructive pressure ulcer surgery. |