Beyond the Usual Suspects: RSV Infection in Patients With Hematological Malignancies Compared to Influenza and SARS-COV-2-A Report From the EPICOVIDEHA/EPIRESEHA Registry

• Authors: SALMANTON-GARCIA Jon; MARCHESI Francesco; NAVRATIL Milan; FALCES-ROMERO Iker; ILARIA Del Principe Maria; LABRADOR Jorge; PIUKOVICS Klara; PETZER Verena; BIERNAT Monika M; SAMARKOS Michail; LEOTTA Dario; FRACCHIOLLA Nicola; DABROWSKA-IWANICKA Anna; VENA Antonio; VISEK Benjamin; BILGIN Yavuz M; JENS Van Praet; PAPA Mario Virgilio; INMACULADA Heras Fernando; FARINA Francesca; DRGONA Lubos; BATINIC Josip; WEINBERGEROVÁ Barbora; ERBEN Nurettin; DROZD-SOKOLOWSKA Joanna; GARCIA-RAMIREZ Patricia; CUCCARO Annarosa; CERNAN Martin; SGHERZA Nicola; LAHMER Tobias; VINH Donald C; PLANTEFEVE Gaetan; LOPEZ-GARCIA Alberto; CATTANEO Chiara; PANTIC Nikola; KHOSTELIDI Sofya; DAVILA-VALLS Julio; SOTO-SILVA Andres; PINCZES Laszlo Imre; MAGYARI Ferenc; KHEDR Reham Abdelaziz; DARGENIO Michelina; BAKKER Martijn; STOMA Igor; GARCIA-VIDAL Carolina; ESPIGADO Ildefonso; CERCHIONE Claudio; BUQUICCHIO Caterina; STOJANOSKI Zlate; MAGLIANO Gabriele; GRAFE Stefanie K; AUJAYEB Avinash; PREZIOSO Lucia; OTASEVIC Vladimir; MERELLI Maria; MACKENZIE Erica; GLENTHOJ Andreas; GAVRIILAKI Eleni; EISA Noha; DELIA Mario; BUSCA Alessandro; ALMASARI Ahlam; ADZIC-VUKICEVIC Tatjana; UROSEVIC Ivana; SILI Uluhan; MIRANDA-CASTILLO Carolina; MENDEZ Gustavo-adolfo; MEERS Stef; MARCHETTI Monia; COPPOLA Nicola; COLAK Gokce Melis; ANTIC Darko; HERSBY Ditte Stampe; MUSTO Pellegrino; CVETANOSKI Milche; SCHONLEIN Martin; AIELLO Tommaso Francesco; ARELLANO Elena; NAPPI Davide; MARTIN-PEREZ Sonia; MITROVIC Mirjana; CORDOBA Raul; PRIN Romane; CALLEJAS-CHARAVIA Marta; VARRICCHIO Gina; BAVASTRO Martina; LIMONGELLI Alessandro; ANASTASOPOULOU Amalia N; ROMANO Alessandra; WOLF Dominik; NGUYEN Kevin; LUKAS Van Den Ven; ALESSIA Di Pilla; GIORDANO Antonio; CORNELY Oliver A; PAGANO Livio
• Year of publication: 2026
• Type: Peer-reviewed scientific article
• Magazine / Source: American Journal of Hematology
• MU Faculty or unit: Faculty of Medicine
• web: https://onlinelibrary.wiley.com/doi/10.1002/ajh.70166
• Doi: https://doi.org/10.1002/ajh.70166
• Keywords: hematological malignancy; neglected; opportunistic infection; real-world data; respiratory syncytial virus
• Description: Respiratory syncytial virus (RSV) is a major cause of acute re-spiratory infections and seasonal hospitalisations, particularlyamong immunocompromised adults. In patients with hema-tological malignancies, RSV can cause severe complications,including pneumonia, respiratory failure, and death, especiallyin those with lymphopenia, recent HSCT, or comorbidities .Although antivirals, monoclonal antibodies, and vaccines existfor other high-risk groups, their efficacy in this populationremains uncertain. Screening and diagnostic protocols areinconsistent, treatments are often empiric, and hematologicalpatients are largely excluded from clinical trials. Moreover, com-parative data versus influenza and SARS- CoV-2 are limited, im-peding the development of targeted, evidence-based preventionand management strategies for this vulnerable group.