Publication details
Arterial Stiffness in Asthmatic Children: A Pilot Study
| Authors | |
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| Year of publication | 2026 |
| Type | Appeared in Conference without Proceedings |
| Citation | |
| Description | Asthma bronchiale (AB) is a common chronic inflammatory disease that may exert systemic effects, especially on the cardiovascular system. This pilot study evaluated arterial stiffness and central hemodynamics in children with AB compared with healthy controls. Fifty-nine asthmatic patients and fifty-seven age-matched controls underwent pulse wave analysis and carotid–radial pulse wave velocity (crPWV) measurement. In the control group, all parameters remained within physiological ranges; however, asthmatic children showed significantly higher crPWV and lower subendocardial viability ratio (SVI). Age-stratified analysis revealed the most pronounced differences in older adolescents, who demonstrated increased systolic and diastolic blood pressure, augmentation pressure, and further elevation of crPWV, accompanied by reduced SVI. These findings suggest early subclinical vascular alterations in asthmatic children, potentially reflecting chronic inflammation. Early recognition of such changes may support cardiovascular risk monitoring and highlight the need for longitudinal studies to determine their long-term clinical implications. |
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