Publication details

Implementation and First Results of the Czech Nationwide Prostate Cancer Screening Pilot Program

Investor logo
Investor logo
Authors

KOUDELKOVÁ Marcela HEJCMANOVÁ Kateřina BABJUK Marek ZACHOVAL Roman FERDA Jiri BRATT Ola CHLOUPKOVÁ Renata NGO Ondřej HEJDUK Karel VÁLEK Vlastimil DUŠEK Ladislav MÁJEK Ondřej

Year of publication 2026
Type Peer-reviewed scientific article
Magazine / Source EUROPEAN UROLOGY OPEN SCIENCE
MU Faculty or unit

Faculty of Medicine

Citation
web https://www.sciencedirect.com/science/article/pii/S2666168326006543?via%3Dihub
Doi https://doi.org/10.1016/j.euros.2026.07.003
Keywords Cancer screening; Early detection; Population; Prostate cancer; Prostate-specific antigen; Screening
Description Background: In 2022, the European Union recommended piloting organized prostate cancer screening. Subsequently, the Czech Republic launched a nationwide pilot program fully reimbursed by public health insurance in January 2024 to reduce the high incidence of late-stage prostate cancer and the widespread unorganized prostate-specific antigen (PSA) testing. Objective: To describe the strategy, methodology, and first results of the Czech nationwide prostate cancer screening pilot program. Design, setting, and participants: We analyzed data from the first 12 mo of the program targeting men aged 50-69 yr without a previous diagnosis of prostate cancer. General practitioners and urologists offer men an initial PSA test. Those with PSA >= 3.0 lg/l are referred to certified urologists. Based on urology assessment, selected for magnetic resonance imaging (MRI) and, if indicated, targeted biopsy. Outcome measurements and statistical analysis: Reported key indicators are PSA testing coverage and overall use of prebiopsy MRI. Results and limitations: Screening was offered to 150 498 men; PSA results were available for 146 109 (97.1%) men, 8.8% of whom had PSA >= 3.0 lg/l. Within 6 mo, 67.2% of the men with PSA >= 3.0 lg/l underwent urological evaluation. From 2023 to 2024, the 2-yr PSA testing rate rose from 47.4% to 53.3%, and pre-biopsy MRI use increased from 28.0% to 38.3% (10.3 percentage-point difference, 95% confidence interval 8.3-12.2). Data on diagnostic outcomes are not yet analyzed.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info