Publication details
Effect of very high bromide intake on iodine metabolism in the rat
| Authors | |
|---|---|
| Year of publication | 2000 |
| Type | Article in Periodical |
| Magazine / Source | Chemické Listy [IF=0.278 (1999)] |
| MU Faculty or unit | |
| Citation | |
| Field | Endocrinology, diabetology, metabolism, nutrition |
| Keywords | bromide; iodine; metabolism; rat |
| Description | The influence of an enhanced bromide intake on the uptake of 131-I by the thyroid and various organs and tissues of rats, on the magnitude of the whole-body biological half-life of iodine, and on the body weight and prosperity of rats was followed with the help of radionuclide tracer techniques. Based on the results obtained, we conclude that a high level of bromide in the organism can obviously influence the iodine metabolism in two parallel ways: by a competitive inhibition of iodide accumulation in the thyroid, and by accelerating the iodine excretion by the kidney. |
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