Publication details

Columnar Packing of Telomeric Nucleosomes

Authors

FAJKUS Jiří TRIFONOV Edward N.

Year of publication 2001
Type Article in Periodical
Magazine / Source Biochemical and Biophysical Research Communications
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Keywords Columnar Packing;Telomeric Nucleosomes
Description Telomeres belong to the key functional elements of eukaryotic chromosomes. Like all the other parts of the genome, they exist and function as complexes of DNA with histones and various nonhistone proteins, including specific telomere-binding proteins. Studies of telomeric chromatin have shown on the one hand a lack of nucleosome positioning and on the other hand a specific nucleosome spacing as revealed by micrococcal nuclease digestion. Based on these properties and on accumulated experimental data, we present a model for a columnar packing of nucleosomes in telomeric chromatin. Copyright 2001 Academic Press.
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