Publication details

Distribution of the RAGE gene polymorphisms in patients with chronic periodontitis: a preliminary study

Authors

IZAKOVIČOVÁ HOLLÁ Lydie KAŇKOVÁ Kateřina FASSMANN Antonín BUČKOVÁ Dana HALABALA Tomáš ZNOJIL Vladimír VANĚK Jiří

Year of publication 2001
Type Article in Periodical
Magazine / Source J Periodontol
MU Faculty or unit

Faculty of Medicine

Citation
Field ORL, ophthalmology, stomatology
Keywords gene; polymorphism; RAGE; periodontitis
Description Periodontal diseases are viewed today as multifactorial problems that are initiated and sustained by bacteria but significantly modified by the body's response to bacterial plaque. Recent study suggested that RAGE (receptor for advanced glycation end products) could be involved in the pathophysiology of periodontitis. The aim of this study was to investigate a possible association of three common polymorphisms in the RAGE gene with adult periodontitis.
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