Publication details
One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano-phenyl)benzimidoyl isothiocyanate
| Authors | |
|---|---|
| Year of publication | 2001 |
| Type | Article in Periodical |
| Magazine / Source | Molecules |
| MU Faculty or unit | |
| Citation | |
| Field | Organic chemistry |
| Keywords | 1-(2-phenylquinazolin-4-yl)-3-substituted thioureas; quinazolines; thioureas; benzimidoyl isothiocyanates |
| Description | 1-substituted-3-(2-phenylquinazolin-4-yl) thioureas were produced by an intramolecular cycloaddition reaction of 1-substitued-3-[(2-cyanophenylimino)phenyl-methyl]thioureas. These compounds in turn were prepared by a domino reaction of N-(2-cyanophenyl)benzimidoyl isothiocyanate with primary amines. The structures of products were confirmed by FTIR, 1 H-NMR, 13 C-NMR, mass spectroscopy and X-ray crystallography. |
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