Publication details

Baroreflex sensitivity, blood pressure and heart rate variability in children and adolescents after anthracycline treatment.

Authors

HRSTKOVÁ Hana HONZÍKOVÁ Nataša FIŠER Bohumil NOVÁKOVÁ Zuzana

Year of publication 2001
Type Article in Periodical
Magazine / Source Scripta medica
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords Leukaemia; anthracycline; baroreflex sensitivity; blood pressure; age
Description Age related changes of systolic (SBP) and diastolic (DBP) blood pressure, mean cardiac interval (PI) and baroreflex sensitivity in ms/mmHg (BRS) and in Hz/mmHg (BRSf) after anthracycline treatment were monitored. The values of 20 children treated with anthracyclines were compared with those treated with a non-anthracycline medication (16 patients) and 177 health controls.The age-dependent increase of SBP, DBP, PI and the decrease of BRSf were observed in all groups. The age-dependent increase of SBP was decelerated in children treated with anthracycline.
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