Publication details

Induced differentiation and apoptosis in HL-60 cell line modulated by caffeic acid treatment

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Authors

VESELSKÁ Renata ZITTERBART Karel AUER Jan

Year of publication 2002
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description The aim of presented study was to investigate possible effect of caffeic acid (CA) in combination with known differentiating agents, all-trans retinoic acid (ATRA) or dimethylsulfoxide (DMSO) respectively, on the HL-60 human myeloid leukemia cell line. Treatment of the HL-60 cells by CA in combination with known differentiation inductors ATRA and DMSO leads to the reduction of cell viability and increased frequency of apoptosis.
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