Publication details
The role of the serotonergic system in experimental drug dependence
Authors | |
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Year of publication | 2002 |
Type | Article in Periodical |
Magazine / Source | Scripta medica |
MU Faculty or unit | |
Citation | |
Field | Pharmacology and pharmaceutical chemistry |
Keywords | 5-HT receptor agonists; 5-HT receptor antagonists; diazepam; methamphetamine; "i.v. drug self-administration"; "drug discrimination"; agonistic behaviour;mice;rats |
Description | Thu study presents the utilization of behavioural experimental models to assess the role of serotonin neurotransmitter brain system in withdrawal signs occurred after ending of chronic diazepam treatment, and in rat methamphetamine dependence. The results referred bring the evidence about a possible preventive action of serotonergics from the occurrence of withdrawal signs while pre-treated prior to diazepam repeated administration withdrawal. |
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