Publication details
Differential effects of v-Jun and c-Jun proteins on v-myb-transformed monoblasts
| Authors | |
|---|---|
| Year of publication | 2002 |
| Type | Article in Periodical |
| Magazine / Source | Cellular and Molecular Life Sciences |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | v-Myb; Jun; differebtiation; proliferation; retinoic acid; phorbol ester |
| Description | The line of v-myb-transformed chicken monoblats BM2 can be induced to terminal differentiation using phorbol esters. The fact that Jun proteins are up-regulated in the phorbol ester-treated BM2 cells promptred us to investigate the role of the Jun proteins in regulation of myeloid differentiation. We ectopically expressed v-jun and c-jun in BM2 cells and evaluated their effects on differentiation, proliferation and apoptosis. |
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