Publication details

VYUŽITIE ZVIERACIEHO MODELU DEPRESIE PRI OVEROVANÍ ANTIDEPRESÍVNYCH ÚČINKOV FELBAMÁTU

Title in English The animal model of depression in testing antidepressant effects of felbamate
Authors

PISTOVČÁKOVÁ Jana ŠULCOVÁ Alexandra

Year of publication 2003
Type Article in Proceedings
Conference Abstrakta 47. Studentské vědecké konference
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords felbamate - animal model - antidepressant - olfactory bulbectomy
Description Repeated administration of felbamate (240 mg/kg/day) elicited a significant inhibition of the motor hyperactivity in the rat model of depression (Olfactory Bulbectomy Model), which indicates a potential antidepressant felbamate effects. At the same time, the significantly suppressed leukocyte phagocytosis recorded in bulbectomized rats was disinhibited by felbamate treatment.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info