Publication details

Vliv předozáření na některé biochemické parametry maligních nádorů mléčné žlázy: receptory steroidních hormonů

Title in English Influence of pre-irradiation on some biochemical parameters of breast malignant tumors: steroid hormone receptors
Authors

LANG B.A. ČERNOCH M. ŠIMÍČKOVÁ M. NEKULOVÁ M. FORBELSKÁ Marie PECEN L. EBEN K. VONDRÁČEK J. PAČOVSKÝ Z. VERMOUSEK I.

Year of publication 2001
Type Peer-reviewed scientific article
Magazine / Source Klinická onkologie
MU Faculty or unit

Faculty of Science

Citation
Field Oncology and hematology
Keywords breast cancer; estrogen-receptor; progesterone-receptor; radiotherapy; cancer cell; ionizing radiation
Description Our results confirm the differences in the expression of steroid hormones in malignant breast tumours with and without pre-irradiation. The results seem to support the assumption that preoperative irradiation of breast tumours may impair the function of estrogen a progesterone signalling pathways in the tumour tissue. The authors believe that a thorough understanding of the consequences irradiation may produce in both healthy and oncologically affected tissue of the mammary gland remains a clinically topical issue even today.
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