Publication details
Differentiation of brown adipose tissue and biogenesis of thermogenic mitochondria in situ and in cell culture
| Authors | |
|---|---|
| Year of publication | 1990 |
| Type | Article in Periodical |
| Magazine / Source | Biochimica et Biophysica Acta [IF=2.411 (1989); SCI #cit.<22>] |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | Biogenesis; brown adipose tissue; differentiation; mitochondrion; thermogenesis; uncoupling protein |
| Description | Differentiation and biogenesis of mitochondria in brown adipose tissue (BAT) was studied in situ and in cell culture by Western blotting, enzyme activity measurements, [35S]methionine incorporation and immuno-fluorescence microscopy. The biogenesis was characterized by the sudden appearance and rapid increase of the uncoupling protein (UCP), increase of cytochrome oxidase (COX) and decrease of H+ -ATPase. |