Informace o publikaci
Differentiation of brown adipose tissue and biogenesis of thermogenic mitochondria in situ and in cell culture
| Autoři | |
|---|---|
| Rok publikování | 1990 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Biochimica et Biophysica Acta [IF=2.411 (1989); SCI #cit.<22>] |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Genetika a molekulární biologie |
| Klíčová slova | Biogenesis; brown adipose tissue; differentiation; mitochondrion; thermogenesis; uncoupling protein |
| Popis | Differentiation and biogenesis of mitochondria in brown adipose tissue (BAT) was studied in situ and in cell culture by Western blotting, enzyme activity measurements, [35S]methionine incorporation and immuno-fluorescence microscopy. The biogenesis was characterized by the sudden appearance and rapid increase of the uncoupling protein (UCP), increase of cytochrome oxidase (COX) and decrease of H+ -ATPase. |