Informace o publikaci
Differentiation of brown adipose tissue and biogenesis of thermogenic mitochondria in situ and in cell culture
Autoři | |
---|---|
Rok publikování | 1990 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Biochimica et Biophysica Acta [IF=2.411 (1989); SCI #cit.<22>] |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Genetika a molekulární biologie |
Klíčová slova | Biogenesis; brown adipose tissue; differentiation; mitochondrion; thermogenesis; uncoupling protein |
Popis | Differentiation and biogenesis of mitochondria in brown adipose tissue (BAT) was studied in situ and in cell culture by Western blotting, enzyme activity measurements, [35S]methionine incorporation and immuno-fluorescence microscopy. The biogenesis was characterized by the sudden appearance and rapid increase of the uncoupling protein (UCP), increase of cytochrome oxidase (COX) and decrease of H+ -ATPase. |