Publication details

Comparison of acoustic densitometry and dobutamine echocardiography in the assessment of myocardial viability



Year of publication 2004
Type Article in Periodical
Magazine / Source European Journal of Echocardiography
MU Faculty or unit

Faculty of Medicine

Field Cardiovascular diseases incl. cardiosurgery
Keywords acoustic densitometry; viability; coronary artery disease
Description Aim: The purpose of this study has been to compare acoustic densitometry and dobutamine echocardiography for an assessment of myocardial viability. Methods: Fifty-four patients with coronary artery disease and dysfunctional myocardial segments, who were referred for myocardial revascularization, underwent a viability assessment using acoustic densitometry. Thirty-four patients underwent also low-dose dobutamine echocardiography. Amplitude of cyclic variation of integrated backscatter (CVIB) was evaluated from each dysfunctional segment. The receiver operating characteristics curve analysis was applied to determine the optimal cut off value of CVIB for distinction between viable and nonviable dysfunctional myocardium. Results of the two techniques were compared to follow-up resting echocardiography, which was performed at a mean of 3 months after successful revascularization in order to assess the recovery of function in revascularized, initially dysfunctional segments. Echocardiography was performed in standard views using 16-segment model of the left ventricle. Viable myocardium was identified by the augmentation of systolic thickening of an abnormal segment by at least one grade during dobutamine infusion or by the value of the maximal amplitude of cyclic variation of integrated backscatter (CVIB). Results: Acoustic densitometry had the sensitivity and specificity to predict functional recovery 90% and 77%, respectively. Dobutamine echocardiography had the sensitivity and specificity to predict contractile reserve 83% and 81%, respectively. The results were statistically comparable. Concordance between these methods was 80%. Conclusion: Acoustic densitometry and dobutamine echocardiography have comparable sensitivities and specificities for the prediction of functional recovery after coronary revascularization.
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