Publication details

Nové trendy v léčbě schizofrenie

Title in English New Trends in the Therapy of Schizophrenia
Authors

ČEŠKOVÁ Eva

Year of publication 2005
Type Article in Periodical
Magazine / Source Česká a Slovenská psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Psychiatry, sexuology
Keywords schizophrenia; remission; compliance
Description Before the psychopharmacological era, the main aims of treatment were the improvement of self-care, reduction of aggression and self-injury. After the arrival of antipsychotics(AP) the aims of treatment have been becomming more ambitious. Nowadays, remission,improvement of functioning and quality of life are the goals. Remission is defined in terms of symptoms, similarly to affective disorders. Remission is significantly connected with compilance(adherence to the treatment). Studies dealing with these problems suggest that about two thirds of patients do not take AP as prescribed, or even do not take them at all. The ADHES study was aimed at psychiatrists understanding of factors leading to insufficient adherence. Questionnaire-based naturalistic survey that incorporated 80 psychiatrists and 820 of their patients has found that Czech psychiatristsopinions do not differ from those of psychiatrists from other countries.The incidence of partial compliance and noncompliance has been evaluated in accordance with the available literature. Psychiatrists judged that the impairment of cognitive functioning,life conditions and stigma were important factors in about half of their patients, in smaller proportion of patients it was co-morbid substance abuse. With the availability of atypical AP(with better tolerability), long-acting atypicals(positive influence of compliance) and continuous psychoeducation, remission becomes an attainable clinical goal.
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