Publication details

Interakce účinků extáze, metamfetaminu a kanabinoidů v animálních modelech

Title in English Interactions of the ecstasy, methamphetamine and cannabinoids effects in animal models
Authors

LANDA Leoš ŠLAIS Karel KUČEROVÁ Jana ŠULCOVÁ Alexandra

Year of publication 2006
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Repeated administration of MDMA elicited in mice in the open field test both development and expression of sensitization. Repeated pre-treatment by CB1 receptor agonist led to cross-sensitization to the MDMA challenge dose and, in contrary, repeated administration of CB1 receptor antagonist+MDMA suppressed this phenomenon. We did not confirm our hypothesis, that repeated administration of MDMA would sensitise to antiaggressive effects in the mice model of agonistic behaviour.
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