Publication details
Experimentální plicní embolie nezměnila koncentraci mozkového natriuretického peptidu (BNP) u laboratorního potkana.
| Title in English | Experimental pulmonary embolism (PE) did not change brain natriuretic peptide (BNP) levels in a rat model. |
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| Authors | |
| Year of publication | 2005 |
| Type | Article in Periodical |
| Magazine / Source | Cor et Vasa |
| MU Faculty or unit | |
| Citation | |
| web | http://www.coretvasa.cz/pp/obsah/moreinfo?maid=3547&idm=678#3547 |
| Field | Animal diseases, veterinary medicine |
| Keywords | BNP pulmonary embolism rat |
| Description | The aim of this study was to investigate the plasma levels of rat BNP-32 at 60 minutes after pulmonary embolism (PE) induction in an newly developed animal model of sublethal massive non-thrombotic acute PE, and to describe alterations in the evaluated clinical parameters. We have developed a new hemodynamically stable animal model of non-thrombotic acute pulmonary embolism. In this rat model, acute pure/non-thrombotic pulmonary embolism did not change the plasma levels of BNP sampled at 60 minutes after PE introduction. Pulmonary embolism resulted in a significant decrease of SpO2 and heart rate, whilst respiratory rate increased. |