Publication details
Platinum(V) Complex with Adamantylamine as Nonleaving Amine Group: Synthesis, Characterization, and in Vitro Antitumor Activity against a Panel of Cisplatin-Resistant Cancer Cell Lines
| Authors | |
|---|---|
| Year of publication | 2004 |
| Type | Article in Periodical |
| Magazine / Source | Journal Medicinal Chemistry |
| MU Faculty or unit | |
| Citation | |
| Field | Immunology |
| Keywords | Platinum(V) Complex with Adamantylamine as Nonleaving Amine Group |
| Description | Procedure of the synthesis is dedescribed for new platinum(V) drug LA-12 [(OC-6-43)-bis-(acetato)(1-adamantylamine)amminedichloroplatinum(IV)]. The X-ray diffraction analysis shows that the structure is created by molecules with octahedral arrangement of ligands around a platinum atom and contains one H2O molecule that is not a part of the coordination sphere of platinum. |
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