Publication details

Impact of cannabinoid receptor ligands on behavioural sensitization to antiaggressive methamphetamine effects in the model of mouse agonistic behaviour

Authors

LANDA Leoš ŠLAIS Karel ŠULCOVÁ Alexandra

Year of publication 2006
Type Article in Periodical
Magazine / Source Neuroendocrinology Letters
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords methamphetamine; cannabinoids; behavioural sensitization; aggressiveness; mice
Description Repeated administration of methamphetamine elicited a significant sensitization to its antiaggressive effects. Methanandamide pre-treatment provoked cross-sensitization to this methamphetamine effect, whereas pre-treatment with JWH 015 did not. Combined pre-treatment with methamphetamine+AM 251 suppressed the sensitization to antiaggressive effects of methamphetamine.
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