Publication details

Modelling of block of cardiac transient outward current in open channel state



Year of publication 2006
Type Article in Proceedings
Conference Analysis of Biomedical Signals and Images.
MU Faculty or unit

Faculty of Medicine

Field Biophysics
Keywords transient outward current; open channel block; model; rate constants
Description A new procedure is proposed to estimate the rate constants related to the interaction of channels responsible for cardiac transient outward current with drugs that bind to the receptor in open channel state. Its correctness is verified by simulations on a quantitative model of drug-channel interaction.
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