Publication details

Dynamika tvorby protilátek u myší po imunizaci celobuněčným borreliovým antigenem a CpG jako adjuvans

Title in English Dynamics of antibodies production in mice after immunization with whole-cell borrelia antigen using CpG as an adjuvans
Authors

HUBINKA Vít DUŠKOVÁ Monika SLÁMOVÁ Ivana ŽÁKOVSKÁ Alena

Year of publication 2007
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
Description After repeated immunization of mice with whole-cell borrelia antigen we observed increase of the total IgG plasma level. Addition of CpG oligodeoxynucleotides as the adjuvans caused almoust twofold increasing of the IgG plasma level when compare with the group treated with antigen only. We also observed influence of CpG on the dynamic of IgG production: maximal level of IgG was achived three weeks earlier than with antigen alone.
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