Publication details

Organization of nano-scale synthetic oligonucleotides on immersed electrode surface: an optical study.



Year of publication 2007
Type Article in Proceedings
Conference Technical digest
MU Faculty or unit

Faculty of Medicine

Field Biophysics
Keywords diffractive optical element; permittivity; optical roughness; electrode surface;
Description Organization of nano-scale molecules as oligodeoxynucleotides (ODN) or blood plasma proteins attached on electrode surface, which is located in liquids, is an interesting phenomenon. Thus the need to develop novel methods to detect this organization is arisen from the observation that conventional surface characterization methods and tools are observed to be un-effective when a need is to make observation from a sample in a liquid. We report results from our recent investigations, which are extended to sense organization of nano-scale molecules adhered on electrode surface. The permittivity change and the fluctuations in optical roughness of an electrode surface is investigated through an optical window of an cuvette by using the DOE sensor, when the molecules injected in the immersion liquid are adsorbed on the electrode surface.
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