THE ASSOCIATION OF INTERLEUKIN-4 (IL-4) HAPLOTYPES WITH CHRONIC PERIODONTITIS IN A CZECH POPULATION

• Authors: IZAKOVIČOVÁ HOLLÁ Lydie; FASSMANN Antonín; AUGUSTÍN Peter; HALABALA Tomáš; ZNOJIL Vladimír; VANĚK Jiří
• Year of publication: 2008
• Type: Article in Periodical
• Magazine / Source: J Periodontol
• MU Faculty or unit: Faculty of Medicine
• Field: ORL, ophthalmology, stomatology
• Keywords: periodontitis; gene; polymorphism; IL-4; interleukin; haplotype
• Description: Cytokine gene polymorphisms are known to influence susceptibility and disease course of many chronic disorders. Recently, interleukin-4 (IL-4) gene polymorphisms have been associated with aggressive periodontitis. The aim of this study was to test differences in distribution of the IL-4 alleles, genotypes and haplotypes between patients with chronic periodontitis (CP) and healthy controls in a Czech population.

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