Publication details
VYUŽITÍ DETEKCE CYTOKINŮ PŘI PŘÍPRAVĚ VAKCÍN PROTI
| Title in English | ROLE OF CYTOKINE QUANTIFICATION IN PREPARATION OF CELLULAR |
|---|---|
| Authors | |
| Year of publication | 2008 |
| Type | Article in Periodical |
| Magazine / Source | Klinická onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | dendritic cells; multiple myeloma; interleukine 12; interleukine 10; ELISA; Cytometric Bead Array |
| Description | Cytokines mediate intercellular interactions and their quantifi cation represents an important instrument of modern immunology and cell biology used for studies of cell-to-cell communication, including an immune response. This study demonstrates two ways of heterodimeric p70 interleukin 12 (IL-12p70) and IL-10 measurement using conventional ELISA and the novel and highly sensitive Cytometric Bead Array method during the preparation of clinical grade dendritic cell-based vaccine for patients with multiple myeloma. |
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