Publication details
Construction of mutant lectins from Chromobacterium violaceum and study of changes in their binding properties
| Authors | |
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| Year of publication | 2009 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | The aim of this work is in vitro creation of mutant lectins from oportunistic human pathogen Chromobacterium vioalceum. Substitution of amino acids in the lectin structure should lead to changes of lectin sugar specificity. Mutation were focused on the "specificity binding loop" in the position 22-23-24 and in other position 97. The work is going to be followed by structural and functional analysis. |
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