Publication details

Vývoj radiometrických metod pro stanovení enzymových aktivit jodothyronin dejodas: Vliv antidepresiva fluoxetinu na aktivity dejodas typu 1, 2 a 3 v mozku potkana

Title in English Development of radiometric methods for determination of enzyme activities of iodothyronine deiodinases: The influence of antidepressant drug fluoxetine on the types 1, 2 and 3 deiodinase activities in the rat brain
Authors

PAVELKA Stanislav

Year of publication 2010
Type Article in Proceedings
Conference Radioanalytické metody IAA 09 (Vobecký M., ed.)
MU Faculty or unit

Faculty of Science

Citation
Web http://www.spektroskopie.cz
Field Pharmacology and pharmaceutical chemistry
Keywords Antidepressant drug; deiodinase; radiometric assay
Description The objectives of the present study were to establish valid assay conditions for measurement of the types 1, 2 and 3 iodothyronine deiodinases activities, and to use the radiometric enzyme assays especially to follow the effects of antidepressant drug fluoxetine (Prozac) on the metabolism of thyroid hormones in the rat.
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