Publication details

Genome-Wide Reduction in H3K9 Acetylation During Human Embryonic Stem Cell Differentiation

Authors

KREJČÍ Jana UHLÍŘOVÁ Radka GALIOVÁ Gabriela KOZUBEK Stanislav ŠMIGOVÁ Jana BÁRTOVÁ Eva

Year of publication 2009
Type Peer-reviewed scientific article
Magazine / Source Journal of cellular physiology
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Keywords acetylation; stem cell; H3K9; epigenetics
Description In this study, we analyzed H3K9 acetylation, an epigenetic mark associated with transcriptionally active chromatin, during endoderm-like differentiation of hESCs. ChIP-on-chip analysis revealed that differentiation results in a genome-wide decrease in promoter H3K9 acetylation.

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