Publication details

Genome-Wide Reduction in H3K9 Acetylation During Human Embryonic Stem Cell Differentiation

Authors

KREJČÍ Jana UHLÍŘOVÁ Radka GALIOVÁ Gabriela KOZUBEK Stanislav ŠMIGOVÁ Jana BÁRTOVÁ Eva

Year of publication 2009
Type Article in Periodical
Magazine / Source Journal of cellular physiology
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Keywords acetylation; stem cell; H3K9; epigenetics
Description In this study, we analyzed H3K9 acetylation, an epigenetic mark associated with transcriptionally active chromatin, during endoderm-like differentiation of hESCs. ChIP-on-chip analysis revealed that differentiation results in a genome-wide decrease in promoter H3K9 acetylation.

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