Elektrochemická charakterizace krátkých oligonukleotidů

• Title in English: Electrochemical characterization of short oligonucleotides
• Authors: BALCAROVÁ Zdeňka; NEPLECHOVÁ Kamila; TRNKOVÁ Libuše
• Year of publication: 2010
• Type: Article in Proceedings
• Conference: XXX. moderní elektrochemické metody - sborník přednášek
• MU Faculty or unit: Faculty of Science
• Field: Electrochemistry
• Keywords: heptaoligonucleotides; hairpin structure; voltammetry; elimination voltammetry with linear scan
• Description: This study deals with the description and characterization of two heptanucleotides (DNA and RNA) forming hairpin structures. We studied their electrochemical behavior by means of cyclic voltammetry (CV) and elimination voltammetry with linear scan (EVLS) in combination with adsorptive stripping. According to preliminary results we found differences between heptadeoxyribonucleotide and its RNA analog.

Related projects

• Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
• Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine