Publication details

Structural basis of the affinity for oligomannosides and analogs displayed by BC2L-A, a Burkholderia cenocepacia soluble lectin

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Authors

LAMEIGNERE Emilie SHIAO Tze Chieh ROY Rene WIMMEROVÁ Michaela DUBREUIL Fréderic VARROT Annabelle IMBERTY Anne

Year of publication 2010
Type Article in Periodical
Magazine / Source Glycobiology
MU Faculty or unit

Faculty of Science

Citation
Doi http://dx.doi.org/10.1093/glycob/cwp151
Field Biophysics
Keywords bacterial lectin;Burkholderia cenocepacia;mannose;oligosaccharides
Description The disaccharides and the trisaccharide,Man1-3(Man1-6)Man were tested by titration microcalorimetry in order to evaluate their affinity for BC2L-A in solution and to characterize the thermodynamics of the binding. Oligomannose analogs presenting two mannoside residues separated by either flexible or rigid spacer where also tested.
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