Publication details

Use of 125I-labeled iodothyronines as tools for studies of Fluoxetine interaction with the metabolism of triiodothyronine

Authors

PAVELKA Stanislav

Year of publication 2010
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Science

Citation
Description In studies of the interaction of an antidepressant drug fluoxetine with the metabolism of thyroid hormones in the rat, we applied adapted radiometric enzyme assays for iodothyronine sulfotransferases and uridine 5-diphospho-glucuronyltransferase, as well as our newly developed radiometric assays for iodothyronine deiodinases of types 1, 2 and 3, using [I-125]-labeled iodothyronines as substrates.
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