Publication details

Diagnostika a výsledky chirurgické léčby infekční endokarditidy

Title in English The diagnosis of infective endocarditis and outcomes of its surgical treatment.
Authors

POL Jiří ČERNÝ Jan ONDRÁŠEK Jiří ŽALOUDÍKOVÁ Barbora VRŠANSKÝ Dušan FREIBERGER Tomáš NĚMEC Petr

Year of publication 2010
Type Article in Periodical
Magazine / Source cor et Vasa
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords Infective endocarditis; Diagnosis of infective endocarditis; PCR-based diagnostics
Description Based on investigations of blood culture, culture and PCR-based examination of specimens obtained intraoperatively, the etiologic agent of IE was identified in 98 (83.8%) cases. The sensitivity of detection was highest with PCR-based examination (77.8%) and lowest with culture of intraoperatively recovered specimens (22.2%). Seven patients died within one month, and 16 patients within one year of surgery, resulting in 30-day and one-year mortality rates of 6.2% and 14.2%, respectively. A total of 89 patients were alive after five years resulting in a 78.8% five-year survival rate. Four patients (3.5%) had surgery for relapse of endocarditis. While no significant difference was found in the five-year survival of patients with native-valve versus prosthetic-valve endocarditis, there was a trend toward poorer survival rates in those with the latter condition.