Publication details

The atherogenic index of plasma is increased by hormonal contraception

Authors

SOŠKA Vladimír FIALA Jindřich NEBESKÁ Kateřina JARKOVSKÝ Jiří HRUBÁ Drahoslava

Year of publication 2011
Type Article in Periodical
Magazine / Source SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.3109/00365513.2011.553240
Field Cardiovascular diseases incl. cardiosurgery
Keywords Oral contraceptives; dyslipidemias; cardiovascular diseases; risk factors; HDL cholesterol; triglycerides; C-reactive protein
Description The aim of this study was to determine if hormonal contraceptives affect the new atherogenic index of plasma (AIP) = log[triglycerides (TG)/high-density lipoprotein cholesterol (HDL-C)] together with the total cholesterol/HDL-C (TC/HDL-C) and the apolipoprotein B/apolipoprotein A1 (apoB/apoA1) ratios. The increased AIP and hs-CRP concentration after 9 months of hormonal contraception demonstrate that contraceptive-induced dyslipidemia has a proatherogenic nature, even when the TC/HDL-C and the apoB/apoA1 ratios are unchanged.
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